Week Four: September 28, 2008 at Jacksonville Municipal Stadium.
Jacksonville 30, Houston 27 in overtime.
Jaguars QB David Garrard threw for 236 yards with a touchdown then added 41 ground yards and a touchdown as Jacksonville kicked a field goal with 11:25 field goal in overtime to beat Houston. The Texans dropped to 0-3 and the Jaguars improved to 2-2.