Panama City (Spanish: Panamá) is the capital and largest city of the Republic of Panama. It has a population of 813,097, with a total metro population of 1,206,792, and it is located at the Pacific entrance of the Panama Canal. The city is the political and administrative center of the country.Panama City has numerous tourist attractions including world-class hotels and restaurants. Particularly interesting for tourists are various sites located in the old quarter (also commonly referred to as "Casco Viejo", "Casco Antiguo" or "San Felipe").

The area immediately east of the Pacific entrance of the canal—known as the Amador Causeway—is being developed as a major tourist center. Currently the Smithsonian Tropical Research Institute operates a station and a small museum open to the public at Culebra Point on the island of Naos. A new museum, The Bridge of Life Museum, is under construction on the causeway. The Bridge of Life Museum was designed by the American architect Frank Gehry famous for the Guggenheim Museum Bilbao and the Disney Concert Hall in Los Angeles.