Delcambre actually sits on the boundary between Iberia to the east and Vermilion to the west. It is a shrimping community, with a large fleet of small shrimp boats operating in nearby Vermilion Bay and the Gulf of Mexico.

The town dates back to the deal between Spain and France in the 1790's. Almost all of the town was flooded by the tidal surge from Hurricane Rita in 2005. Rita and the problems caused by her were vastly overshadowed by Hurricane Katrina which hit New Orleans a few months before.