1DMkII with RRS L-plate, 70-200/2.8L IS attached to camera, or 24-70/2.8 attached to camera, (whichever lens is not attached is stored on the side), 50/1.4, 550EX Flash, small AA charger, blower bulb, misc small stuff. Another short lens about 5" long could easily be stacked on top of the 50/1.4.
I did have to remove the thickest of the two foam pads on the bottom of the case in order to close the zipper. The remaining bottom pad is closed cell foam and it does provide adequate protection. I also had to cut a 7" tall divider down to 6" to accomodate the tripod foot on the 70-200 lens.
The yellow pads are cut from a foam swimming noodle. The 3" tall pad goes under the 24-70 lens to help support the weight of the camera. Thin noodle pads allow easy stacking of lenses or other stuff. Very convenient and much faster than using the supplied velcro dividers for stacking.