The Hyatt Regency Chicago is a 246 foot tall Hyatt hotel on East Wacker Drive in Chicago, Illinois. The hotel operates over 2,000 guest rooms in two different towers. The towers are connected by both an above-ground skyway and an underground concourse. This underground concourse is considered to be part of the Chicago Pedway.

Rooms that face North have an unobstructed view of the Chicago River. Rooms that face East may be able to see Lake Michigan but the view is obstructed by both Columbus Plaza and another building. Rooms facing West have a view of Illinois Center. Rooms facing South may be able to see other areas of The Loop but may be obstructed by the Park Millennium Condominiums or Illinois Center. All rooms have a view of the streets below.