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Cigarette smoking can deplete vitamin C levels in the body, so an additional 35 mg beyond the RDA is recommended for smokers. The Tolerable Upper Intake Level is the optimal everyday intake unlikely to cause harmful results on health. The UL for vitamin C is 2000 mg daily; taking beyond this quantity may promote gastrointestinal distress and diarrhea.

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The intestines have a limited ability to take in vitamin C. Studies have actually shown that absorption of vitamin C decreases to less than 50% when taking quantities higher than 1000 mg. In usually healthy adults, megadoses of vitamin C are not harmful since when the body's tissues end up being saturated with vitamin C, absorption declines and any excess quantity will be excreted in urine.

Absorption does not differ if obtaining the vitamin from food or supplements. Vitamin C is sometimes given as an injection into a vein (intravenous) so greater amounts can directly enter the bloodstream. This is usually only seen in medically kept an eye on settings, such as to improve the lifestyle in those with sophisticated stage cancers or in controlled clinical studies.

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Vitamin C is involved with many metabolic responses in the body, and getting the RDA or slightly higher may be protective against specific illness states. However, Check For Updates of taking bigger quantities has actually not been discovered in people who are typically healthy and well-nourished. Cell research studies have shown that at really high concentrations, vitamin C can change roles and serve as a tissue-damaging pro-oxidant instead of an anti-oxidant.

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12 Foods with More Vitamin C than Oranges - Chicago Health

There is interest in the antioxidant function of vitamin C, as research study has found the vitamin to reduce the effects of complimentary radical molecules, which in excess can damage cells. Vitamin C is also involved in the body's body immune system by promoting the activity of white blood cells. Does this translate to defense from specific diseases? Persistent diseases Although some epidemiological studies that follow big groups of individuals gradually have found a protective effect of greater intakes of vitamin C (from food or supplements) from cardiovascular illness and particular cancers, other studies have not.