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The money is going to drive it." "It's simply discouraging to believe that there's something that might be helping people and we're not utilizing it," said Dr. Nancy Rigotti, director of the Tobacco Treatment Unit at Massachusetts General Healthcare Facility. A natural product like cytisine can not be patented. That makes its market position harder to defend.


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Drug business say the cost of developing and getting approval for a new drug is $1 billion. This may discuss why some business have actually seen blockbuster profits with treatments for unusual diseases, such as Genzyme's drug for Goucher disease, which costs $300,000 a year. "They're focused on patent defense and new drugs," Stewart said.


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One is the limited cytisine supply. A competitor would require to plant large orchards of laburnum trees numerous thousands of them and wait 4 years before the drug-containing seeds could be harvested. The other thing is that Extab is new to the U.S. market. Nobody has actually ever tried to get it authorized.


market exclusivity as a novel drug under the 1984 Hatch-Waxman Act. That's less than the normal 20-year window for trademarked medicines. But it's something. "It's a truly old, unique drug," Stewart says. Still, he required help getting the drug through the U.S. regulative labyrinth. He required to get fortunate. And he did.


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In 2011, the findings were published in the New England Journal of Medicine, revealing cytisine was 3. 4 times most likely than placebo to help people quit smoking and stay that method for one year, on par with Chantix. Then benefits of quitting smoking by University of Sheffield researchers compared cytisine with Chantix and concluded that while more examination was required, "Cytisine is estimated to be both more medically effective and cost-efficient than (Chantix)." However the real turning point came in December, when another study was published in the New England Journal of Medication.





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