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The Facts About Cytisine for Smoking Cessation: A Literature Review and a Revealed

Still Images/ Getty Images A low-cost quit-smoking drug offered in Eastern Europe can help cigarette smokers kick the habit, but it's not as effective as more costly medications available in the U.S, a brand-new study discovers. Scientists from University College of London led a study of 740 Polish cigarette smokers who were randomly assigned to attempt the smoking-cessation drug cytisine (Tabex) or placebo for almost a month.

4% of the cytisine group remained smoke-free, while only 2. 4% of the control group were still abstinent. More than triple the advantage? That may appear impressive, but Tabex's success rate pales in comparison to that of varenicline (Chantix), a popular stop-smoking drug offered in the U.S., which studies show assists about 20% of cigarette smokers remain abstinent, compared to about 10% of placebo takers, after 12 months.

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About 4. 6% of cytisine users reported psychiatric problems, compared with 3. 2% of the placebo group, a little increased risk of these unfavorable impacts. (Common negative effects consisted of nausea and stomachache.) Cytisine, which is made from Golden Rain acacia seeds, likewise costs much less than varenicline. It has been sold in Eastern Europe since the 1960s, according to the authors.

Cytisine works by simulating nicotine and binding to acetylcholine receptors in the brain, which can trick the body into thinking it's being exposed to nicotine. While even tabex cytisine warn that it might not be the most effective anti-smoking representative available, they note it might be of help to a particular portion of cigarette smokers, specifically in the developing world.

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And anything that curbs the desire for cigarettes is an advantage for public health. Alice Park is an author at TIME. Find her on Twitter at @aliceparkny. You can likewise continue the conversation on TIME's Facebook page and on Twitter at @TIME.

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The total goals of this study are to 1) examine awareness of interest in the usage of pharmacotherapy for smoking cessation in Croatia and Slovenia, nations in Central Europe with really high smoking frequency, and 2) investigate whether cytisine is at least as possible and effective as varenicline in helping cigarette smokers to quit in a real-life setting: family medicine practices in Croatia and Slovenia.