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The primary goals were to compare the efficacy of extracts of the plant Tribulus terrestris (TT; marketed as Tribestan), in comparison with placebo, for the treatment of guys with erectile dysfunction (ED) and with or without hypoactive libido disorder (HSDD), in addition to to keep an eye on the security profile of the drug.

Stage IV, potential, randomized, double-blind, placebo-controlled scientific trial in parallel groups. This study consisted of 180 males aged in between 18 and 65 years with moderate or moderate ED and with or without HSDD: 90 were randomized to TT and 90 to placebo. Clients with ED and hypertension, diabetes mellitus, and metabolic syndrome were consisted of in the research study.

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Each Tribestan film-coated tablet includes the active substance Tribulus terrestris, herba extractum siccum (35-45:1) 250mg which is standardized to furostanol saponins (not less than 112. 5mg). tribestan received orally 32 film-coated tablets daily after meals, during the 12-week treatment period. At the end of monthly, participants' sexual function, including ED, was assessed by International Index of Erectile Function (IIEF) Questionnaire and International Effectiveness Question (GEQ).

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The primary result step was the change in IIEF rating after 12 weeks of treatment. Complete randomization (random sorting using maximum allowable% variance) with an equal variety of patients in each sequence was used. This randomization algorithm has the restriction that unequal treatment allowance is not enabled; that is, all groups need to have the exact same target sample size.

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All result assessors were also blinded to group allowance. 86 clients in each group completed the research study. The IIEF rating improved substantially in the TT group compared with the placebo group (