Church of the Holy Cross is a Roman Catholic place of worship in downtown Warsaw. Located on Krakowskie Przedmie¶cie Str., directly opposite the main Warsaw University campus. The church is currently run by the Missionary Friars of Vincent de Paul.

The main building was constructed between 1679 and 1696. Its main designer was Jozef Szymon Bellotti, the royal architect at the Royal Court of Poland. The façade was relatively modest and reminded of Renaissance facades of the nearby churches. The two towers surrounding the façade were initially square-cut. Between 1725 and 1737 two late Baroque headpieces designed by Józef Fontana were added. The façade itself was refurbished by Fontana's son, Jakub (in 1756) and ornamented with sculptures by Jan Jerzy Plersch.
It is one of the most notable baroque churches in Warsaw.