This is the chapel of 1771, built over the ruins of the first stone chapel of pilgrimage (1655) whose foundations were recently uncovered.

St. Marguerite Bourgeoys, the first teacher in the colony of Ville-Marie and the founder of the Congregation of Notre Dame, rallied the colonists to build a chapel in 1655. In 1673, returning from France, Bourgeoys brought a wooden image of Our Lady of Good Help; the stone church was completed in 1678. It burned in 1754, the reliquary and statue being rescued.

The chapel now also houses the Marguerite Bourgeoys Museum, dedicated to the life of St. Marguerite Bourgeoys and to the early history of Montreal and the chapel site. Below the chapel, the crypt is being excavated as an archeological site, which visitors can see. First Nations and French colonial artifacts have been discovered, along with the foundations of the first chapel and the fortifications of the colony. The church's prominent spire can also be climbed, offering views of the Old Port and Saint Lawrence River. In 2005, Marguerite Bourgeoys's mortal remains were brought back to the church, where she now lies in the sanctuary.