Bergamot is extensively grown as an ornamental plant both within and outside its native range; it is naturalized further west in the United States and also in parts of Europe and Asia. It grows best in full sun, but tolerates light shade and will thrive in any moist soil that is well-drained. Several cultivars have been selected for different flower color, ranging from white through pink to dark red and purple.

The name Oswego Tea comes from the Oswego Indians who taught the immigrants how to use it for tea after the Boston tea party in 1773. The flowers and leaves are good ingredients for potpourri making.

Note that the bergamot herb is not the source of bergamot oil, used to flavor Earl Grey tea; that comes from the bergamot orange, a Mediterranean citrus fruit.

Bee Balm has a long history of use as a medicinal plant by many Native Americans including the Blackfeet. The Blackfeet Indians recognized this plants strong antiseptic action, and used poultices of the plant for skin infections and minor wounds. A tea made from the plant was also used to treat mouth and throat infections caused by dental caries and gingivitis. Bee Balm is the natural source of the antiseptic Thymol, the primary active ingredient in modern commercial mouthwash formulas. The Winnebago used a tea made from bee Balm as a general stimulant. Bee Balm was also used as a carminative herb by Native Americans to treat excessive flatulence