Palazzo Lanfranchi is an example of one of the best 17th century architecture.
It was built between 1668 and 1672 and was intended to be used as a seminary, later used as a classical lyceum.
It is considered the most representative Baroque building in Matera.
Since 2003 it has been home to the National Museum of Medieval and Modern Art of Basilicata.

The assymetrical facade is devided in half by a cornice.
The lower part features five niches with statues of Our Lady of Mount Carmel and saints.
The upper part has a capital with blind arcades and a central rose window, crowned by a pediment with a clock.