The Padres Hospitalarios de San Juan de Dios began work on the church in the second half of the 17th century, and this continued until the end of the 18th century.The façade is built of sandstone from the ruins of the Roman city of Singilia Barba (located near Antequera), except for the doorway which is made of red limestone from El Torcal.The most important feature of the church is its interior, a treasure of the Andalusian Baroque style thanks to its decoration of intricate white plasterwork with a predominance of plant and animal motifs. These ornamental motifs reach their maximum expression in the vault over the transept, which, particularly by day, commands the attention of its visitors.