The church was built in the XIV century. The altarpiece was made in wood by Gabriel Joly (the same artist who made the altarpiece of the cathedral) in the XVI century. He also made the retable of Saints Cosmas and Damian, in the chapel where the mummies of the Lovers were found.
The church has suffered several reforms along the centuries. Between 1896 and 1902 a great reform was made. The Neomudéjar painting is work of Salvador Gisbert. Matias Abad restored the grillwork. The works were directed by Pablo Monguió. The primitive cloister was substituted by a Neogothic cloister.
The tower is the earliest example of Mudéjar architecture in Teruel. It was built in the XIII century.