Puerto Ayora is a town in central Galápagos, located on the southern shore of Santa Cruz Island. The town is named in honor of Isidro Ayora, an Ecuadorian president. The town is sometimes mistakenly referred to as Santa Cruz. Puerto Ayora is the most populous town in the Galápagos Islands, with more than 12,000 inhabitants. Puerto Ayora has the best developed infrastructure in the archipelago. The larger of the two Galápagos banks, Banco del Pacifico, is located in Puerto Ayora, as well as schools, hotels, restaurants, clothing stores, hardware stores, grocery stores, marine stores, tourist shops and night clubs. It is the best place in Galápagos for communicating with the outside world via numerous cybercafes with Internet access or telephone offices. Puerto Ayora emergency medical facilities include a new hospital opened in 2006 and the island's only hyperbaric chamber.
Home to both the Charles Darwin Foundation and the Galápagos National Park, Puerto Ayora is the center of the Galápagos conservation efforts. Island visitors may visit the Charles Darwin Research Station to learn the history of the islands and future conservation plans.