The Staszic Palace (Polish: Palac Staszica) is a palace on Nowy Swiat Street 72. Today it is the seat of the Polish Academy of Sciences.

The history of the Staszic Palace dates to 1620, when King of Poland Zygmunt III Vasa ordered the construction of a small Eastern Orthodox chapel, as a proper place of burial for the former tsar Vasili IV of Russia and his brother, Dmitry Shuisky, who died in Polish captivity after having been captured several years earlier during the Polish-Muscovite War (1605-1618).

As the population was mostly Catholic, Protestant or Jewish, there was little need for an Orthodox chapel and in 1668 another Polish king, Jan Kazimierz Waza, transferred the chapel to the Dominican Order, who would be caretakers of the building until 1808.

In 1818 the building was purchased by Stanislaw Staszic, a leader of the Polish Enlightenment, who ordered its renovation.
The architect in charge was Antonio Corazzi, who designed the palace in a neoclassical style. After the renovation (1820-1823), Staszic transferred the building to the Society of Friends of Science, the first Polish scientific organization.