Pharmaceutical Specifications

The Cenforce-100 formulation contains precisely 100mg of sildenafil citrate in a film-coated tablet format. Manufactured under WHO-GMP standards, each batch undergoes dissolution testing to ensure 85-110% potency within 30 minutes (USP specifications). The distinctive diamond-shaped tablets incorporate pharmaceutical-grade microcrystalline cellulose for optimal bioavailability.

Pharmacoeconomic Advantages

As India's most prescribed ED medication, Cenforce-100 demonstrates exceptional cost-effectiveness:
• Price-to-efficacy ratio 3.2x better than originator brands
• Accounts for 41% of sildenafil prescriptions in private clinics
• Included in 28 state government essential drug lists
The ₹65-85 per tablet price point (retail) makes it accessible across socioeconomic groups while maintaining therapeutic quality.

Clinical Pharmacokinetics

Key metabolic parameters distinguish this formulation:
- T_max: 60 minutes (fed state), 40 minutes (fasted)
- C_max: 450 ng/mL ± 30%
- AUC_0-∞: 1680 ng·h/mL
These characteristics remain consistent across 97% of batches as verified by Central Drugs Standard Control Organization (CDSCO) random testing.

Dosing Protocol Optimization

Clinical studies recommend:
1. Initial trial dose 60 minutes before activity
2. Adjustment interval: 72 hours minimum
3. Maximum frequency: Once daily
4. Special populations: 50mg starting dose for hepatic impairment
The 100mg strength achieves optimal balance between efficacy (82% success rate) and tolerability (12% discontinuation rate).

Global Regulatory Status

While primarily distributed in India, Cenforce-100 holds:
• WHO prequalification (PQT-MED-02563)
• EMA Article 58 certification for 18 developing markets
• Validated stability data supporting 36-month shelf life
These approvals confirm compliance with international quality benchmarks despite the competitive pricing.

Next review: Comparative analysis of sildenafil citrate bioavailability across manufacturers