Catholic Cathedral is located inside the Castle of Chora and you will meet it in a square after the Byzantine Museum and close to the Ursuline School. It is a monument of a great history since it was built in the 13th century and until now it has undergone several changes. This three-aisled domed basilica is nowadays dedicated to the Hypapante. Entering to the church you will see on the floor several coats of arms of eminent families who also used to be donators. The icon of Virgin Mary Eleousa has a prominent position in the church. It dates back to the 11th century while the bilateral face of the Virgin Mary holding Jesus Child is a work of art of an extraordinary historical significance along with the icon of the Saint John the Baptist, located on the other side.