When patients ask what is Amoxil, they're inquiring about one of the most commonly prescribed antibiotics worldwide. Amoxil (amoxicillin) is a semi-synthetic penicillin derivative that revolutionized bacterial infection treatment when introduced in 1972.
Scientific Classification
Property |
Description |
Chemical Class |
Aminopenicillin |
Molecular Formula |
C16H19N3O5S |
Mechanism |
Bactericidal (cell wall inhibitor) |
Key Characteristics
- Acid-stable: Survives stomach acid for oral administration
- Broad-spectrum: More effective against gram-negative bacteria than original penicillins
- Time-dependent killer: Requires maintaining blood levels above MIC
Available Formulations
Standard Preparations
- Oral capsules: 250mg, 500mg
- Chewable tablets: 125mg, 250mg
- Oral suspension: 125mg/5mL, 250mg/5mL
How It Compares to Other Antibiotics
- Vs. penicillin V: Better absorption, broader spectrum
- Vs. azithromycin: More effective against streptococci
- Vs. cephalexin: Better tissue penetration
Important Safety Considerations
- Contraindicated in patients with true penicillin allergy
- Dose adjustment required for renal impairment
- May reduce effectiveness of oral contraceptives
Conclusion
Understanding what is Amoxil provides insight into why it remains a first-line treatment for numerous bacterial infections decades after its introduction. Its optimal balance of effectiveness, safety, and cost continues to make it an indispensable tool in modern antimicrobial therapy.