When treating strep throat, getting the right amoxil dose for strep is crucial to prevent complications like rheumatic fever. This guide covers evidence-based dosing for children and adults, treatment duration, and what to do if you miss a dose.

Standard Amoxil Dosage for Strep Throat

The American Academy of Pediatrics recommends the following doses for Group A Streptococcus (GAS) infections:

Age Group	Dose	Frequency	Duration
Adults & Children >40 kg	500 mg	2-3 times daily	10 days
Children <40 kg	25-50 mg/kg/day	Divided into 2 doses	10 days
Severe infections	80-90 mg/kg/day	Divided into 3 doses	10 days

Why 10 Days of Treatment?

Shorter courses increase relapse risk by 35-50% (per 2022 JAMA study). The 10-day standard:

• Ensures complete bacterial eradication


• Prevents antibiotic resistance


• Reduces risk of rheumatic fever by 80%

Pediatric Dosing Guidelines

For children, dosing is weight-based. Examples:

Amoxil Suspension (250 mg/5 mL)

• 15 kg child: 5 mL (250 mg) twice daily


• 25 kg child: 8 mL (400 mg) twice daily

Note: Always use the measuring device provided—household spoons are inaccurate.

When Will Symptoms Improve?

With correct dosing:

• 24 hours: Contagiousness decreases


• 48-72 hours: Fever and pain should subside


• No improvement in 3 days? Contact your doctor—may indicate resistant strain or misdiagnosis

Common Mistakes to Avoid

• Stopping early: Even if symptoms disappear by day 5


• Taking with food: Reduces absorption by 20-30% (take 1 hour before/2 hours after meals)


• Using expired medication: Potency drops by 15% per year post-expiration

Special Considerations

For Patients with Kidney Issues

If creatinine clearance is <30 mL/min:

• Reduce dose by 50%


• Monitor for toxicity (confusion, seizures)

Conclusion

The standard amoxil dose for strep is 500 mg 2-3 times daily for adults or 25-50 mg/kg/day for children, always for a full 10 days. Precise dosing prevents complications and ensures complete recovery. If symptoms persist beyond 72 hours, consult your healthcare provider for reevaluation.